Harry C. Dietz
| Born | |
| Died |
Related eponyms
American paediatric geneticist.
Biography of Harry C. Dietz
Harry C. Dietz graduated Bachelor of Science from Duke University in 1980, and obtained his medical doctorate from SUNY Upstate Medical Center in 1984. He served his residency in paediatrics at the Johns Hopkins University 1984-1987 and became a fellow in cardiology at Johns Hopkins Hospital in 1977.
Dietz is a Victor A. McKusick Professor of Genetics in the Departments of Medicine, Pediatrics, and Molecular Biology and Genetics at the Johns Hopkins University School of Medicine, and director of the William S. Smilow Center for Marfan Syndrome Research.
Dietz is a Victor A. McKusick Professor of Genetics in the Departments of Medicine, Pediatrics, and Molecular Biology and Genetics at the Johns Hopkins University School of Medicine, and director of the William S. Smilow Center for Marfan Syndrome Research.
Bibliography
A strategy for disease gene identification through nonsense-mediated mRNA decay inhibition.
F. Noensie and H. C. Dietz. Nature Biotechnology, New York, 2001, 19:434-439
Association of human aging with functional variant of klotho.
D. E. Arking, A. Krebsova, M. Macek Sr, M. Macek Jr, A. Arking, I. S. Mian, L. Fried, A. Hamosh, S. Dey, I. McIntosh, H. C. Dietz.
Proceedings of the National Academy of Sciences of the United States of America, 2002, 99: 856-861.
An mRNA surveillance mechanism that eliminates transcripts lacking termination codons.
P. A. Frischmeyer, A. van Hoof, K. O’Donnell, A. L. Guerrerio, R. Parker, H. C. Dietz.
Science, Washington, 2002, 295 (5563): 2258-2261.
Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts.
J. T. Mendell, C. M. J. ap Rhys, H. C. Dietz.
Science, Washington, 2002, 298: 419-422.
Dysregulation of TGF-ß activation contributes to pathogenesis of Marfan syndrome.
E. R. Neptune, P. A. Frischmeyer, D. E. Arking, L. Myers, T. E. Bunton, B. Gayraud, Ramirez, L. Y. Sakai, H. C. Dietz.
Nature Genetics, New York, 2003, 33 (3): 407-411.
KLOTHO Allele Status and the Risk for Early-Onset Occult Coronary Artery Disease.
D. E. Arking, D. M. Becker, L. R. Yanek, D. Fallin, D. P. Judge, T. F. Moy, L. C. Becker, H. C. Dietz. The American Journal of Human Genetics, Chicago, 2003, 72: 1154-1161.
Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome.
D. P. Judge, N. J. Biery, D. R. Keene, J. Geubtner, L. Myers, D. L. Huso, L. Y. Sakai, H. C. Dietz.
The Journal of Clinical Investigation, Ann Arbor, MI , 2004, 114: 172-181.
Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise.
J. T. Mendell, N. A. Sharifi, J. L. Meyer, F. Martinez-Murillo, H. C. Dietz.
Nature Genetics, New York, October 2004, 36 (10):1073-1078. Erratum: November 2004, 36 (11): 1238 2004.
TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome.
C. M. Ng, A. Cheng, L. A. Myers, F. Martinez-Murillo, C. Jie C, D. Bedja, K. L. Gabrielson, J. M. W. Hausladen, R. P. Mecham, D. P. Judge, H. C. Dietz.
The Journal of Clinical Investigation, Ann Arbor, MI ,2004, 114 (11): 1586-1592.
A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGF beta R1 or TGF beta R2.
B. L. Loeys, J. Chen, E. R. Neptune, D. P. Judge, M. Podowski, T. Holm, J. Meyers, C. C. Leitch, N. Katsanis, N. Sharifi, L. Xu, L. A. Myers, J. De Backer, J. Hellermans, Y. Chen, E. C. Davis, C. L. Webb, W. Kress, P. J. Spevak, D. E. Cameron, P. Coucke, D. B. Rifkin, De Paepe, H. C. Dietz.
Nature Genetics, New York, (released online 1/30/05).
F. Noensie and H. C. Dietz. Nature Biotechnology, New York, 2001, 19:434-439
Association of human aging with functional variant of klotho.
D. E. Arking, A. Krebsova, M. Macek Sr, M. Macek Jr, A. Arking, I. S. Mian, L. Fried, A. Hamosh, S. Dey, I. McIntosh, H. C. Dietz.
Proceedings of the National Academy of Sciences of the United States of America, 2002, 99: 856-861.
An mRNA surveillance mechanism that eliminates transcripts lacking termination codons.
P. A. Frischmeyer, A. van Hoof, K. O’Donnell, A. L. Guerrerio, R. Parker, H. C. Dietz.
Science, Washington, 2002, 295 (5563): 2258-2261.
Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts.
J. T. Mendell, C. M. J. ap Rhys, H. C. Dietz.
Science, Washington, 2002, 298: 419-422.
Dysregulation of TGF-ß activation contributes to pathogenesis of Marfan syndrome.
E. R. Neptune, P. A. Frischmeyer, D. E. Arking, L. Myers, T. E. Bunton, B. Gayraud, Ramirez, L. Y. Sakai, H. C. Dietz.
Nature Genetics, New York, 2003, 33 (3): 407-411.
KLOTHO Allele Status and the Risk for Early-Onset Occult Coronary Artery Disease.
D. E. Arking, D. M. Becker, L. R. Yanek, D. Fallin, D. P. Judge, T. F. Moy, L. C. Becker, H. C. Dietz. The American Journal of Human Genetics, Chicago, 2003, 72: 1154-1161.
Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome.
D. P. Judge, N. J. Biery, D. R. Keene, J. Geubtner, L. Myers, D. L. Huso, L. Y. Sakai, H. C. Dietz.
The Journal of Clinical Investigation, Ann Arbor, MI , 2004, 114: 172-181.
Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise.
J. T. Mendell, N. A. Sharifi, J. L. Meyer, F. Martinez-Murillo, H. C. Dietz.
Nature Genetics, New York, October 2004, 36 (10):1073-1078. Erratum: November 2004, 36 (11): 1238 2004.
TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome.
C. M. Ng, A. Cheng, L. A. Myers, F. Martinez-Murillo, C. Jie C, D. Bedja, K. L. Gabrielson, J. M. W. Hausladen, R. P. Mecham, D. P. Judge, H. C. Dietz.
The Journal of Clinical Investigation, Ann Arbor, MI ,2004, 114 (11): 1586-1592.
A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGF beta R1 or TGF beta R2.
B. L. Loeys, J. Chen, E. R. Neptune, D. P. Judge, M. Podowski, T. Holm, J. Meyers, C. C. Leitch, N. Katsanis, N. Sharifi, L. Xu, L. A. Myers, J. De Backer, J. Hellermans, Y. Chen, E. C. Davis, C. L. Webb, W. Kress, P. J. Spevak, D. E. Cameron, P. Coucke, D. B. Rifkin, De Paepe, H. C. Dietz.
Nature Genetics, New York, (released online 1/30/05).