Li-Fraumeni syndrome
Related people
A rare familial syndrome characterized by the occurrence of sarcomas, breast cancer, brain tumours, leukaemia, and adrenocortical tumours in children and young adults.
Bibliography
- F.P. Li, J.F. Freemeni, Jr.:
Soft-tissue sarcomas, breast cancer and other neoplasm's: A familial syndrome?
Annals of Internal Medicine, Philadelphia, October 1969, 71 (4): 747-752. - F.P. Li, J.F. Freemeni, Jr.:
Rhabdomyosarcoma in children: Epidemiologic study and identification of a familial cancer syndrome.
Journal of the National Cancer Institute, Cary, NC, 1969, 43: 1365-1373. - F.P. Li, J.F. Fraumeni, Jr., J.J. Mulvihill:
A cancer family syndrome in twenty-four kindreds.
Cancer Research, September 15, 1988, 48 (18): 5358-5362. - D. Malkin, F.P. Li, L.C. Strong, J.F. Fraumeni, Jr., C.E. Nelson, D.H. Kim, J. Kassel, M.A. Gryka, F.Z. Bischoff, M.A. Tainsky, S.H. Friend:
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.
Science, Washington, November 30, 1990, 250 (4985): 1233-1238. - F.P. Li, J.E. Garber, S.H. Friend, et al:
Recommendations on predictive testing for germ line p53 mutations among cancer-prone individuals.
Journal of the National Cancer Institute, August 5, 1992, 84 (15): 1156-1160 .