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Harjola-Marable syndrome

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A syndrome of compression of the celiac axis. Epigastric crampy pain beginning 30 minutes to 4 hours after eating, not related to type of food. Moderate relief from knee-chest position. Occasionally, nausea, vomiting, diarrhoea, eructation, flatulence. More frequent in young women.

Compression of the celiac artery by extraluminal structures such as arcuate ligament was first detected by Benjamin Lipshutz (1878-1931) in 1917. In 1963, it was described by Harjola as a clinical syndrome of postprandial pain invariably associated with a systolic bruit and other constitutional symptoms such as nausea, vomiting, occasional diarrhea and malabsorption.

Bibliography

  • P. T. Harjola:
    Buffer capacity and acid-base balance of blood; effects of blood loss and some infusion fluids on rabbit blood.
    Annales chirurgiae et gynaecologiae Fenniae. Supplementum, Helsinki, 1960. Supplement 95.
  • P. T. Harjola:
    A rare obstruction of the coeliac artery.
    Annales chirurgiae et gynaecologiae Fenniae, 1963, 52: 547-549.
  • J. D. Dunbar, W. Molnar, F. F. Beman, S. Marable:
    Compression of the celiac trunk and abdominal angina.
    American Journal of Roentgenology, 1965, 95: 731-743.
  • S. A. Marable, W. Molnar, F.M. Beman:
    Abdominal pain secondary to celiac axis compression.
    The American Journal of Surgery, New York, April 1966, 111 (4): 493-495.
  • S. A. Marable, M. F. Kaplan, F. M. Berman, W.Molnar:
    Celiac compression syndrome.
    American Journal of Surgery, New York, January 1968, 115: 97-102.

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