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Schaumann's bodies

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Inclusion bodies composed of calcium and proteins in the giant cells (Langhans’ giant cells) seen in granulomatous conditions such as sarcoidosis and berylliosis. They are rounded, with a diameter of 8-300 µ, made up of concentrically layered lamella. They are easily recognized in infrared light.

These bodies were first described by the German physician Oscar von Schüppel (1837-1881) in 1871, and by Max Askanazy (1865-1940) in 1921 as Kalkdrusen.

Bibliography

  • O. Schüppel:
    Untersuchungen über Lymphdrüsentuberkulose. Tübingen, 1871.
  • M. Askanazy:
    Über lupöse Tuberkulose des Blutbildungsapparates und tuberkulöse Splenomegalie.
    Beiträge zur pathologischen Anatomie und zur allgemeinen Pathologie, 1921, 69: 563-582.
  • J. Schaumann:
    Recherches sur le lupus pernio et sur les relations avec les sarcoides cutanées et sous-cutanées.
    Annales de dermatologie et de syphilographie, Paris, 1917, 5: 357-373.

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